The Big Sick

Kumail Nanjiani

Kumail Nanjiani

Zoe Kazan

Emily Gardner

Holly Hunter

Beth Gardner

Ray Romano

Terry Gardner

Anupam Kher

Azmat Nanjiani

Zenobia Shroff

Sharmeen Nanjiani

Adeel Akhtar

Naveed Nanjiani

Bo Burnham

CJ

Aidy Bryant

Mary

Kurt Braunohler

Chris

Vella Lovell

Khadija

Myra Lucretia Taylor

Nurse Judy

Jeremy Shamos

Bob Dalavan

David Alan Grier

Andy Dodd

Ed Herbstman

Sam Highsmith

Shenaz Treasury

Fatima Nanjiani

Rebecca Naomi Jones

Jesse

Kuhoo Verma

Zubeida

Mitra Jouhari

Yazmin

Celeste Arias

Denise

Shana Solomon

Nurse Bette

Jeff Blumenkrantz

Dr. Wright

Linda Emond

Dr. Cunningham

Holly Chou

Dr. Whelan

Andrew Pang

Dr. Spellman

Alison Cimmet

Dr. Platt

Lawrence Ballard

Dr. Lewin

Shunori Ramanathan

Sumera

Spencer House

Racist Heckler

Susham Bedi

Tina (Khadija's Mother)

Rahul Bedi

Farhan (Khadija's Father)

Matthew Cardarople

Fast Food Cashier

Myra Turley

Waiting Room Person 1

William Stephenson

Waiting Room Person 2

Marilyn Torres

Waiting Room Person 3

Kerry Flanagan

Waiting Room Person 4

Jack O'Connell

Waiting Room Person 5

Charles Gould

Waiting Room Person 6

Isabel Shill

Party Goer 1

Lauren Patten

Party Goer 2

Keilly McQuail

Party Goer 3

Zach Cherry

Party Goer 4

Sophia Muller

Chrissy (uncredited)

Jack Corrigan

Restaurant Boy (uncredited)